Funded by the Horizon 2020 Framework Programme
of the European Union


Exciting Post doc opportunity to study the role of RNA pol III in longevity.

Applications are invited for an independent, forward thinking postdoctoral research fellow with a passion for ageing biology. The research in the Tullet laboratory aims to understand how transcription underpins the plasticity of adult physiology and lifespan in the nematode worm C. elegans. We are interested in a range of components of the eukaryotic transcriptional apparatus, from basal transcriptional machinery (see Filer et al. 2017 Nature) to specific transcription factors (Tullet et al. 2017 Ageing Cell and Tullet et al., 2008) and their role in adult physiology, health and lifespan. The laboratory is part of the School of Biosciences at the University of Kent. This BBSRC-funded project aims to elucidate the molecular mechanisms whereby partial inhibition of RNA polymerase III can extend lifespan in the worm. The long-term aim of this work is to ensure human health and wellbeing throughout the life course. The project will be conducted in collaboration with Dr Nazif Alic (University College London) and Prof. Colin Selman (University of Glasgow).

Full-time indeterminate Research Technician position at Institut Pasteur

The Cecere Laboratory at Insitut Pasteur in Paris is looking for a Research Technician (Full-time indeterminate position) to join their Team in studying the mechanisms underlying epigenetic inheritance in animals. They use the nematode Caenorhabditis elegans to investigate the role of small non-coding RNAs in transmitting epigenetic information across generations. As a Research Technician, you would assist investigators in research activities and carry out assigned laboratory duties according to standard and specified procedures. In addition, you will be in charge of lab management responsibilities, including the maintenance of the worm collection, database of reagents, and equipment maintenance. Specific Requirements: • Molecular biology techniques, including DNA, RNA, protein extraction and purifications, PCR and molecular cloning. • C. elegans maintenance, crossing, and genotyping. • C. elegans transgenesis, including microinjection and screening of transgenic animals. • Basic microscopy manipulation skills. • Strong motivation, commitment, and ability to work independently as well as in a Team. • Excellent organizational skills. • Good oral and written command of English. • Basic knowledge of French is preferred. Qualifications: • Degree in Life Sciences (BSc or equivalent, or a higher degree) • Considerable prior laboratory work experience with C. elegans or similar model organisms. Ideally the candidate will also have experience in one of the following techniques: • Creation of transgenic C. elegans strains by CRISPR and/or MosSCI • Preparation and quantification of libraries for illumina sequencing (ex. RNA-seq) Environment: The candidates will benefit from training in a vibrantly intellectual and collaborative international environment. The expertise of our Team is wide-ranging and complementary, including many genome-wide sequencing methods (small RNA seq, RNA-seq, GRO-seq, CLIP-seq, Ribo-seq), biochemistry and proteomics, and imaging techniques. Applications, including CV and cover letter, should be sent by April 15th, 2019 to: Please, visit our website to know more about our research projects...

Postdoctoral positions in the Ciosk lab, University of Oslo, Norway

We seek outstanding candidates interested in molecular mechanisms regulating body fat and/or stress adaptation. Our lab is at the University of Oslo, the oldest and largest university in Norway. Oslo is the country’s largest city, attractively located between the Oslofjord and forested hills. The city has an abundance of world-class architecture, museums, restaurants and shopping. For more information and to apply see: Postdoc: Researcher: ...