Christian Frøkjær-Jensen
Understanding genome organization through high-throughput genome engineering...
Understanding genome organization through high-throughput genome engineering...
elucidating the mechanisms of toxicity of environmentally relevant compounds...
This constitutes a new research line initiated by Dr. Christian Griñán-Ferré, by using C. elegans, as well as several mice models of neurodegeneration. The research interest is the development of new chemical entities based on epigenetics to ameliorate and prevent neurodegenerative diseases, including brain rare disorders. He is also interested in the implications of the transgenerational epigenetic inheritance in the cognitive decline risk for the next generation. The advanced research projects included G9a/GLP inhibitors....
Investigating the role of mitophagy in the cellular and organismal homeostasis....
Understand how nervous system and behaviour evolves with the age of the anima...
We want to understand if and how animals respond optimally to their environmental and nutritional conditions....
We use C. elegans to study genetic and molecular toxicology....
Characterization of conserved Ubiquitin-modifying enzyme regulating innate immunity...
We investigate the molecular mechanisms of sexual dimorphism from synapses and circuits to the behavioral outputs....
Our group aims at understanding how environmental stress, particularly nutrients availability, affects the state, spatial compartmentalization and function of chromatin using C. elegans as a model organism....
We study RNA modifications and their role in germ cell proliferation and differentiation. ...
The laboratory for bioanalytical chemistry develops novel analytical techniques to decipher the ecology and evolution of small molecule signaling and secondary metabolism in nematodes....
The research in our lab focuses on dissecting the complex interactions between pharmacological compounds, diet, gut microbes and host physiological processes responsible for health and disease....
We are examining the interallelic interactions of NPHS2 mutations in C. elegans....
The use of transgenic Caenorhabditis elegans and gene expression analysis to understand Endocrine Disrupting Chemicals (EDCs) toxicity and Danube Delta bio-monitoring...