Funded by the Horizon 2020 Framework Programme
of the European Union

Cell fate specification

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Rodriguez, Josana

We study the molecular mechanisms that underlie cell polarity using a combination of high-throughput protein interaction mapping approaches and in vivo studies using the model organism C. elegans....

Poole, Richard

We investigate the regulatory logic of early neural specification and asymmetric neurogenesis using forward genetic screens, 4D-lineage screens and promoter analysis....

Pintard, Lionel

Our lab is interested in understanding how the cell cycle is regulated during development....

Gotta, Monica

The interest of my lab is to dissect the molecular mechanisms underlying the process of asymmetric cell division. We study how polarity is established and maintained, how the mitotic spindle is properly formed and oriented and how these processes are coordinated with other events of the cell cycle....

Wicky, Chantal

Transcription factors and chromatin modifiers are important in programming and reprogramming cell fate during development. We are investigating the function of the chromatin remodeler LET-418/Mi-2, which is part of at least two protein complexes, the NuRD and the MEC complexes involved in the development of the nematode Caenorhabditis elegans....

Doitsidou, Maria

How is a nervous system made in a developing organism? Why do nerve cells die during aging or in cases of disease and how can we stop this from happening? ...

Ciosk, Rafal

I have a general interest in elucidating the molecular mechanisms controlling cell fate maintenance and reprogramming. We focus on the germline-soma dichotomy, elucidating both cytoplasmic and nuclear determinants controlling the commitment to the germ cell fate and the reprograming to pluripotency....

Pocock, Roger

My research focuses on how the diversity of fates and morphologies of the nervous system are generated....

Poulin, Gino

The main interest of the Poulin lab is to understand how signalling events occurring in the extracellular space can produce a response inside the cell to impact on the chromatin structure. This can release the transcriptional machinery for activation or prevent its engagement for repression....

Barkoulas, Michalis

The major research interest in my newly established laboratory concerns the relationship between genotype and developmental phenotypes and how the environment modifies this relationship....

Cochella, Luisa

One of the main goals of developmental biology is to understand how the different cell types that constitute a multicellular organism are specified during its development....

Flames, Nuria

Our lab is interested in understanding how neuronal diversity is established and maintained. We also aim to explore if this processes are linked to genetic association to mental disorders....

Yanai, Itai

By comparing the genetic programs of different animals, at the molecular level, our research seeks to discover the principles by which evolution achieves this feat. Our lab at the Technion is composed of developmental, molecular, and computational biologists....

Grosshans, Helge

MicroRNAs (miRNAs) are a large and important class of regulatory RNAs that silence target mRNAs through an antisense mechanism. They function in diverse developmental processes such as apoptosis and cell differentiation, and their dysregulation has been implicated in various diseases, especially cancers....

van Zon, Jeroen

My research group uses a quantitative, physics-inspired approach to study problems in developmental biology, focusing on C. elegans. The aim of the research is to elucidate how living organisms build their bodies during development in a robust manner....