Patrick Laurent
Understand how nervous system and behaviour evolves with the age of the anima...
Understand how nervous system and behaviour evolves with the age of the anima...
Control of cell proliferation and arrest in response to the nutritional state of multicellular organisms...
Molecular mechanisms that establish neuronal microtubule cytoskeleton...
Our main research objective is to elucidate how nucleosome organization is related to chromatin function....
Regulation of the actomyosin cytoskeleton during cellular and tissue morphogenesis...
Understanding the role of cell mechanical properties for physiology and disease....
Mechanisms of extracellular vesicle release and uptake in early embryonic development....
We study the molecular mechanisms that underlie cell polarity using a combination of high-throughput protein interaction mapping approaches and in vivo studies using the model organism C. elegans....
We investigate the regulatory logic of early neural specification and asymmetric neurogenesis using forward genetic screens, 4D-lineage screens and promoter analysis....
Our lab is interested in understanding how the cell cycle is regulated during development....
My team works on the general theme of the role of the cytoskeleton in cell motility and cell shape changes. We use in vitro bead systems coupled with the study of simple cell and tissue movements from the model organism Caenorhabditis elegans to probe the interplay between biochemical activity and biophysical behavior...
Transcription factors and chromatin modifiers are important in programming and reprogramming cell fate during development. We are investigating the function of the chromatin remodeler LET-418/Mi-2, which is part of at least two protein complexes, the NuRD and the MEC complexes involved in the development of the nematode Caenorhabditis elegans....
We are interested in the symbiosis between Wolbachia endosymbionts and onchocercidae, a family of parasitic nematodes causing debilitating filariasis in tropical areas....
Our lab is located within a Hospital, which implies a biomedical orientation. We have two main interests: characterise function of genes whose orthologs has been relates to disease and cancer...
Life expectancy is variable in many organisms, including laboratory strains of C. elegans that are isogenic. My group is focused on understanding the causes the underly the variability in lifespan. ...