Krieg, Michael
Understanding the role of cell mechanical properties for physiology and disease....
Understanding the role of cell mechanical properties for physiology and disease....
Mechanisms of extracellular vesicle release and uptake in early embryonic development....
My lab's main focus is on embryonic morphogenesis. First, we try to elucidate the regulation of cytokinesis during embryogenesis with the aim to better understand cytokinesis' impact on morphogenetic processes. ...
Our lab is interested in understanding how the cell cycle is regulated during development....
My team works on the general theme of the role of the cytoskeleton in cell motility and cell shape changes. We use in vitro bead systems coupled with the study of simple cell and tissue movements from the model organism Caenorhabditis elegans to probe the interplay between biochemical activity and biophysical behavior...
Transcription factors and chromatin modifiers are important in programming and reprogramming cell fate during development. We are investigating the function of the chromatin remodeler LET-418/Mi-2, which is part of at least two protein complexes, the NuRD and the MEC complexes involved in the development of the nematode Caenorhabditis elegans....
We are interested in the symbiosis between Wolbachia endosymbionts and onchocercidae, a family of parasitic nematodes causing debilitating filariasis in tropical areas....
Worldwide it is estimated that 15% of couples have problems conceiving. A likely primary cause for poor germ cell quality is aneuploidy (a wrong number of chromosomes in the cell)....
Pattern-forming systems provide essential spatial cues to guide the complex three dimensional puzzle that is organismal development. Work over the past decades has identified most of the key molecules involved, yet we are only beginning to understand how the collective activities of these molecules give rise to patterns at the cell and tissue scale....
The main interest of the Poulin lab is to understand how signalling events occurring in the extracellular space can produce a response inside the cell to impact on the chromatin structure. This can release the transcriptional machinery for activation or prevent its engagement for repression....
To what extent is it possible to predict the phenotypic differences amongst individuals from their completely sequenced genomes? We use model organisms (particularly C. elegans) and computational analyses to understand when you can, and why you cannot, predict the biology of an individual from their genome sequence alone....
One of the main goals of developmental biology is to understand how the different cell types that constitute a multicellular organism are specified during its development....
By comparing the genetic programs of different animals, at the molecular level, our research seeks to discover the principles by which evolution achieves this feat. Our lab at the Technion is composed of developmental, molecular, and computational biologists....
My research group uses a quantitative, physics-inspired approach to study problems in developmental biology, focusing on C. elegans. The aim of the research is to elucidate how living organisms build their bodies during development in a robust manner....