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Gene expression

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Ahringer, Julie

We investigate the regulation of chromatin function and gene expression in C. elegans....

Chen, Ron

The main objective of our research programme is to understand chromatin function and gene regulation....

Sar, Funda

My laboratory is working on the roles of miRNAs and LincRNAs in 1) stress responses, 2) protein homeostasis, and 3) ageing....

Sturzenbaum, Stephen

Some molecules are exclusively toxic to biological systems and others are essential for life; their interplay are vital drivers of well being, longevity and survival. Nevertheless, above certain threshold concentrations all compounds (including essential ones) become toxic....

Riedel, Christian

Lifespan is largely determined by the rate at which we age. In the Riedel laboratory we use the nematode Caenorhabditis Elegans as a model system to understand the pathways that can accelerate or impair this process. C. Elegans is ideal for ageing-related research, as it is technically well established, short-lived (allowing for lifespan as an easily measurable phenotype), and very responsive to alterations in its ageing-regulatory pathways....

Dalfó, Esther

My research is focused on the use of the nematode to study neurodegeneration. My two neurodegeneration topics are a) fatty acid accumulation defects and its role in neurodegeneration and b) contributing factors to the development of synucleinoapthies. ...

Wicky, Chantal

Transcription factors and chromatin modifiers are important in programming and reprogramming cell fate during development. We are investigating the function of the chromatin remodeler LET-418/Mi-2, which is part of at least two protein complexes, the NuRD and the MEC complexes involved in the development of the nematode Caenorhabditis elegans....

Landmann, Frederic

We are interested in the symbiosis between Wolbachia endosymbionts and onchocercidae, a family of parasitic nematodes causing debilitating filariasis in tropical areas....

Ceron, Julian

Our lab is located within a Hospital, which implies a biomedical orientation. We have two main interests: characterise function of genes whose orthologs has been relates to disease and cancer...

Casanueva, Olivia

Life expectancy is variable in many organisms, including laboratory strains of C. elegans that are isogenic. My group is focused on understanding the causes the underly the variability in lifespan. ...

Doitsidou, Maria

How is a nervous system made in a developing organism? Why do nerve cells die during aging or in cases of disease and how can we stop this from happening? ...

Schuster, Eugene

Recent ageing studies have revealed that ageing can be regulated and even more surprising is that many of the classic signaling pathways that have been exhaustively studied for many years are involved in the regulation of ageing....

Swoboda, Peter

We are using a worm, the tiny soil nematode Caenorhabditis elegans, as a model system to study nervous system development per se and also as it relates to humans....

Ciosk, Rafal

I have a general interest in elucidating the molecular mechanisms controlling cell fate maintenance and reprogramming. We focus on the germline-soma dichotomy, elucidating both cytoplasmic and nuclear determinants controlling the commitment to the germ cell fate and the reprograming to pluripotency....

Pocock, Roger

My research focuses on how the diversity of fates and morphologies of the nervous system are generated....