Genomics

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Cecere, Germano

In our laboratory, we are studying the role of small RNAs in epigenetic inheritance and in transcriptional regulation during animal development. ...

29 November, 2017 / 0 Comments

Sturzenbaum, Stephen

Some molecules are exclusively toxic to biological systems and others are essential for life; their interplay are vital drivers of well being, longevity and survival. Nevertheless, above certain threshold concentrations all compounds (including essential ones) become toxic....

26 September, 2014 / 0 Comments

Brown, Andre

The goal of behavioural genomics is to understand the mapping between genome variation and behaviour. However, technology for sequencing and perturbing genomes is advancing more rapidly than our ability to assess all of the consequences of genetic perturbation....

26 September, 2014 / 0 Comments

Schumacher, Björn

We are interested in the mechanisms through which genome instability causally contributes to cancer development and ageing. We are employing the nematode system to identify cellular and systemic response mechanisms to DNA damage....

25 September, 2014 / 0 Comments

Gross, Einav

In our lab we try to understand how oxygen homeostasis is regulated. We study this question at all levels; from the organismal to the molecular; we combine optogenetics, genetics, biochemical, and behavioral techniques....

25 September, 2014 / 0 Comments

Landmann, Frederic

We are interested in the symbiosis between Wolbachia endosymbionts and onchocercidae, a family of parasitic nematodes causing debilitating filariasis in tropical areas....

25 September, 2014 / 0 Comments

Teotonio, Henrique

We are interesting in understanding the consequences of different reproductive systems to the population and quantitative genetics of adaptation to novel environments....

25 September, 2014 / 0 Comments

Ceron, Julian

Our lab is located within a Hospital, which implies a biomedical orientation. We have two main interests: characterise function of genes whose orthologs has been relates to disease and cancer...

25 September, 2014 / 0 Comments

Casanueva, Olivia

Life expectancy is variable in many organisms, including laboratory strains of C. elegans that are isogenic. My group is focused on understanding the causes the underly the variability in lifespan. ...

25 September, 2014 / 0 Comments

Doitsidou, Maria

How is a nervous system made in a developing organism? Why do nerve cells die during aging or in cases of disease and how can we stop this from happening? ...

25 September, 2014 / 0 Comments

Schuster, Eugene

Recent ageing studies have revealed that ageing can be regulated and even more surprising is that many of the classic signaling pathways that have been exhaustively studied for many years are involved in the regulation of ageing....

25 September, 2014 / 0 Comments

Swoboda, Peter

We are using a worm, the tiny soil nematode Caenorhabditis elegans, as a model system to study nervous system development per se and also as it relates to humans....

25 September, 2014 / 0 Comments

Poulin, Gino

The main interest of the Poulin lab is to understand how signalling events occurring in the extracellular space can produce a response inside the cell to impact on the chromatin structure. This can release the transcriptional machinery for activation or prevent its engagement for repression....

19 September, 2014 / 0 Comments

Lehner, Ben

To what extent is it possible to predict the phenotypic differences amongst individuals from their completely sequenced genomes? We use model organisms (particularly C. elegans) and computational analyses to understand when you can, and why you cannot, predict the biology of an individual from their genome sequence alone....

19 September, 2014 / 0 Comments

Flames, Nuria

Our lab is interested in understanding how neuronal diversity is established and maintained. We also aim to explore if this processes are linked to genetic association to mental disorders....

19 September, 2014 / 0 Comments