Samantha Hughes
elucidating the mechanisms of toxicity of environmentally relevant compounds...
elucidating the mechanisms of toxicity of environmentally relevant compounds...
Investigating the role of mitophagy in the cellular and organismal homeostasis....
My research aims to understand the causative role of protein misfolding in neurodegenerative diseases...
Understanding the role of cell mechanical properties for physiology and disease....
Our group research interest is to o reveal the potential effects and molecular targets of pre-clinical agents on several diseases, such as neurodegenerative diseases, diabetes and cancer....
Our research focuses on the molecular mechanisms of necrotic cell death and neurodegeneration, the interplay between cellular metabolism and ageing, the mechanisms of sensory transduction and integration by the nervous system, and the development of novel genetic tools for biomedical research....
Our lab aims to identify these regulatory mechanisms and to evaluate how physiological protein aggregation impacts the health of the organism during aging and in the context of disease....