I am generally interested in how physiological functions are integrated at a whole-organism level, with a particular emphasis on gut biology.
I wish to understand how animals and their microbiome communicate throughout life to maintain homeostasis. To probe such interactions, I study C. elegans and its adult gut microbiota under challenging conditions (infection, stress, ageing). Combining genome-wide phenotyping screens, RNAseq and in chip time-lapse imaging, I aim to map the genetic network that govern worm gut-bacteria interactions. In parallel, I also study the neuromuscular regulation of death in C. elegans in a bid to identify interventions that can halt or delay tissue decay and organismal death.
Start Lab in 2016