Funded by the Horizon 2020 Framework Programme
of the European Union

Alexandre Benedetto

member since 2017

I am generally interested in how physiological functions are integrated at a whole-organism level, with a particular emphasis on gut biology.

I wish to understand how animals and their microbiome communicate throughout life to maintain homeostasis. To probe such interactions, I study C. elegans and its adult gut microbiota under challenging conditions (infection, stress, ageing). Combining genome-wide phenotyping screens, RNAseq and in chip time-lapse imaging, I aim to map the genetic network that govern worm gut-bacteria interactions. In parallel, I also study the neuromuscular regulation of death in C. elegans in a bid to identify interventions that can halt or delay tissue decay and organismal death.

Start Lab in 2016

Lancaster University
Division of Biomedical and Life Sciences
Bailrigg, Lancaster, LA1 4YW
United Kingdom


Lancaster University
Division of Biomedical and Life Sciences
Bailrigg, Lancaster, LA1 4YW
United Kingdom