Investigate the roles of genes associated with Ciliopathies. Understand the molecular basis underlying decision making.
Understanding the mechanistic roles of disease-associated genes especially those linked to Ciliopathies, a group of human genetic diseases caused by defective cilia.
Additionally, the aim of our lab is to advance our understanding of the molecular basis of decision making process. What allows humans to think and make a decision has been one of the most challenging questions. During daily life every person make countles decisions and in order make a decision, someone must take into account of positive and negative sides of each alternatives. From a scientific perspective there is a growing need to better understand genetic mechanisms underlying decision making. Understanding molecular basis of decision making is interesting not only for scientists but also a range of professions including doctors, economists and politicians.We will use the gene expression databases coupled with the comparative genomics (decision making vs non-decision making) to predict the genes potentially responsible for decision making and then will employ the nematode Caenorhabditis elegans, one of the most studied model organisms, and perform experiments to confirm our predictions. We can learn a lot about the molecular basis of decision making by looking at genetic codes of decision making and non-decision making organisms
Start Lab in 2016