Modeling human Diseases in C. elegans : RNA processing and cancer
Our lab is located within a Hospital, which implies a biomedical orientation. We have two main interests:
1) Characterise function of genes whose orthologs has been relates to disease (let say “oriented basic research”). We are particularly interested in genes involved in RNA metabolism (splicing, stress granules, degradation) and we also have a project related to chromatin remodelling SWI/SNF subunits.
2) The second main interest in cancer, and we are collaborating with other researchers in our institution to validate functional interactions between genes related to cancer, and to identify genes that confer resistance or sensitivity to chemotherapeutical agents.
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