Actin dynamics and biomechanics of the early embryo.
Since September 2017 at IGBMC, my goal is to combine interdisciplinary approaches to reveal how actin related cortical biomechanical properties control cell specification during the early C. elegans embryonic development. This involves first identifying universal processes and regulatory mechanisms that control the assembly and dynamics of the cell cortex. Second to determine how these properties are transmitted to daughter cells or how they evolve with regards to the first cell specifications. To do so I combine my interdisciplinary expertise at the interface of biochemistry, cell biology and physics and develop novel approaches combining both in vivo and in vitro tools. This will allow us to cross scales from molecules to large-scale coherent material and open up new insights into the understanding of the architectural orchestration and regulation of actin cytoskeletal structures.
Start Lab in 2017